Conducting an IHC Study – Factors to Consider: Part 1 Immunohistochemistry (IHC) is a method for demonstrating the presence and location of proteins in tissue. IHC enables the observation of processes in the context of intact tissue, which is especially useful for assessing the progression and treatment of certain diseases. Immunohistochemical staining is accomplished with […]
The Histological Analysis of Implantable Medical Devices Resin/Plastic Sectioning vs Cutting and GrindingResin/plastic histology is typically used to examine hard tissue such as bone and implanted medical device interaction with surrounding tissues. There are two basic methodologies: grinding, also called cutting and grinding, and sectioning, which is done on a rotary microtome. In either method, […]
Conducting Biocompatibility Testing for a Medical Device: Part II Interview with Jeff Geesin, Research Director & Medical Device Consultant About Jeff GeesinJeff Geesin is a biochemist with extensive experience in corporate research and technical expertise in extracellular matrix biology, wound repair and regeneration, tissue engineering/regenerative medicine, and preclinical models of disease for testing therapeutic approaches. […]
Challenges Faced by Medical Device Companies: Part II Interview with Ian McDougall, CEO of Evasc Medical SystemsAbout Ian McDougall, BASc President & CEO of Evasc Medical Systems Ian has an engineering degree from the University of British Columbia and has been working in the medical device sector for over 14 years. He has co-founded several […]
Biocompatibility of Implants/Medical Devices Histological evaluation is the preferred method to examine the in situ interaction between the implanted device and surrounding tissues. With paraffin histology, it is difficult to maintain the device/tissue interaction when examining the interface between two materials. This difficulty arises as a result of the differences in density and material properties […]
