Table of Contents 1. Introduction to Western Immunoblot Western Immunoblot (often referred to simply as Western Blot) is a widely used technique for detecting specific proteins in a sample. It involves the separation of proteins based on size through gel electrophoresis and then transferring them to a membrane. This allows researchers to study the presence […]
Table of Contents What is Imaging and Analysis? Imaging and Analysis is a broad field that encompasses various techniques and technologies used to capture visual data and process it for the purpose of diagnosing, monitoring, and researching various diseases and conditions. The field of imaging refers to the creation of visual representations of the interior […]
Preclinical Pathology Services: A Cornerstone of Biomedical Research Preclinical pathology services are a vital component of medical research, especially in the development of new treatments and therapies. They involve the use of pathology techniques to study and evaluate disease mechanisms in animal models before clinical trials on humans begin. Pathology plays a critical role in […]
Table of Contents What is Immunohistochemistry (IHC)? Immunohistochemistry (IHC) is a powerful laboratory technique used to identify specific antigens (proteins) in tissues. By using antibodies that bind to these antigens, IHC enables medical professionals to visually observe the presence, location, and amount of specific proteins in tissue samples. This technique plays a critical role in […]
Table of Contents What is Tissue Microtomy? Tissue microtomy is a technique used in histology to prepare thin slices of tissue for examination under a microscope. These slices, often just a few micrometers thick, are essential for detailed analysis of the cellular structure of tissue samples. Tissue microtomy is widely used in various fields like […]
Table of Contents 1. Introduction to Tissue Processing Tissue processing is a vital technique in histopathology that prepares tissue samples for further analysis, typically through microscopic examination. This process is used to preserve tissue morphology, allowing scientists to study the cellular structure and identify any abnormalities or diseases. Effective tissue processing ensures that the tissue […]
Table of Contents What is Tissue Grossing in Preclinical Histology? Tissue grossing in a preclinical histology laboratory refers to the meticulous process of preparing tissue samples for microscopic examination, a critical step in research, drug development, and disease diagnosis. This procedure ensures that tissue samples are properly processed for analysis, allowing researchers and pathologists to […]
Immunofluorescence (IF) has emerged as a cornerstone in preclinical research, providing unparalleled insights into cellular and molecular biology. By combining the specificity of antibodies with the vivid detection capabilities of fluorescence microscopy, immunofluorescence enables researchers to visualize proteins, molecules, and structures with remarkable precision. This blog delves into the versatility and applications of immunofluorescence in […]
Immunohistochemistry (IHC) has witnessed significant advancements, solidifying its role as an indispensable tool in preclinical histopathology. These innovations enhance the precision, efficiency, and breadth of applications for immunohistochemistry, providing deeper insights into tissue biology and disease mechanisms. This blog delves into the latest developments and their implications for preclinical research. What is Immunohistochemistry?Immunohistochemistry is a […]
Implanted medical device histopathology has become a cornerstone in evaluating the safety, efficacy, and long-term performance of medical implants. Leveraging resin histology techniques, researchers can achieve detailed insights into the interactions between implanted devices and biological tissues. This article highlights the importance, methodologies, and applications of implanted medical device histopathology, with a special focus on […]
