Immunohistochemistry (IHC)

Step into our world of cutting-edge facilities, where our dedicated team harnesses the latest laboratory innovations to propel preclinical research forward with every tailored IHC program we offer. From pioneering method development to illuminating biomarker discovery, and conducting extensive antibody testing studies, we’re here to elevate your research journey to new heights.

IHC Optimization Program

Our IHC Optimization Program is designed to support the high-quality optimization of IHC and Immunofluorescence (IF) antibodies, enabling the generation of reliable quantitative data essential for preclinical studies. This comprehensive program includes:
Literature Review: Conducting thorough reviews to identify the optimal antibody for your study.
Custom Protocol Development: Tailoring IHC or IF protocols to meet specific study requirements, utilizing our advanced auto stainers for enhanced precision.
Internal Tissue Control Bank: Providing access to a diverse tissue control bank for robust validation of staining protocols.
Digital Whole Slide Scanning: Performing high-resolution whole slide scans of each stained tissue section to ensure detailed analysis.
Optimization Report: Delivering a detailed report with customized staining protocols and images.

Automation in the Lab

The Wax-it IHC department is adept at developing and validating a variety of IHC assays, leveraging our expertise in reagent processes and technological advancements. Our BioCare IntelliPATH FLX Auto stainer and Dako Autostainer Link 48 facilitate an optimized workflow for IHC and IF, ensuring quality services with improved turnaround times.

Research Areas in IHC and IF

Our IHC and IF services span a wide spectrum of research fields, encompassing Immuno-oncology, Fibrosis, Diabetes, Cardiovascular, Dermatology, Neurosciences, Metabolic Disorders, Liver, and Kidney-related studies with continuous endeavors to broaden our expertise. Additionally, we commonly undertake studies related to Dementia, Parkinson's Disease, and Alzheimer's Disease within the realm of Neurological Research.

Access to Internal Tissue Bank and Antibody Validation

We provide access to our internal tissue bank, offering customizable tissue & cell controls and tumor microarrays to ensure reliable outcomes. Our antibody validation programs are conducted in close collaboration with clients, involving our pathologists, image analysis specialists, and statistics teams to provide robust support and ensure compliance with general validation parameters.

Advanced Imaging and Quantification

Our imaging capabilities are designed to offer high-resolution digital whole slide scans, ensuring detailed examination and analysis of each tissue section. Our imaging and quantification facilities for IHC features state-of-the -art equipment such as Leica Aperio AT2 and Zeiss Axioscan 7.