Publications

2024
Metabolic switching, growth kinetics and cell yields in the scalable manufacture of stem cell-derived insulin-producing cells. 2024 Jan 02.

Diepiriye G. Iworima, Robert K. Baker, Cara Ellis, Chris Sherwood, Lisa Zhan, Alireza Rezania, James M. Piret, Timothy J. Kieffer.

2023
Phrenic nerve stimulation mitigates hippocampal and brainstem inflammation in an ARDS model. 2023 May 05.

Thiago G. Bassi, Elizabeth C. Rohrs, Karl C. Fernandez, Marlena Ornowska, Michelle Nicholas, Jessica Wittmann, Matt Gani, Doug Evans, Steven C. Reynolds.

2023
Preclinical PET Imaging and Toxicity Study of a 68Ga-Functionalized Polymeric Cardiac Blood Pool Agent. 2023 Feb 25.

Katayoun Saatchi, François Bénard, Navjit Hundal, Joshua Grimes, Sergey Shcherbinin, Maral Pourghiasian, Donald E. Brooks, Anna Celler, and Urs O. Häfeli.

2022
Host Response of Human Epidermis to Methicillin-Resistant Staphylococcus aureus Biofilm Infection and Synthetic Antibiofilm Peptide Treatment. 2022 Nov 01.

Bing (Catherine) Wu, Travis M. Blimkie, Reza Falsafi, Noushin Akhoundsadegh, Robert E. W. Hancock.

2022
A Mediterranean-like fat blend protects against the development of severe colitis in the mucin-2 deficient murine model. 2022 Apr 26

Natasha Haskey, a Jiayu Ye, a Mehrbod Estaki, b Andrea A. Verdugo Meza, a Jacqueline A. Barnett, a Mitra Yousefi, c Blake W. Birnie, d Samantha Gruenheid, e Sanjoy Ghosh, a and Deanna L. Gibson

2022
Tumor-Suppressor Role of the α1-Na/K-ATPase Signalosome in NASH Related Hepatocellular Carcinoma. 2022 jul 01.

Utibe-Abasi S. Udoh, Moumita Banerjee, Pradeep K. Rajan, Juan D. Sanabria, Gary Smith, Mathew Schade, Jacqueline A. Sanabria, Yuto Nakafuku, Komal Sodhi, Sandrine V. Pierre, Joseph I. Shapiro, and Juan R. Sanabria.

2022
The dietary fiber guar gum ameliorates experimental autoimmune encephalomyelitis via attenuated Th1 activation and differentiation. 2022 Aug 05.

Naomi M Fettig, Hannah G Robinson, Jessica R Allanach, Katherine M Davis, Rachel L Simister, Elsie J Wang, Andrew J Sharon, Ye Jiayu, Sarah J Popple, Jung Hee Seo, Deanna L Gibson, Sean A Crowe, Marc S Horwitz, Lisa C Osborne.

2022
Modulatory role of prenatal alcohol exposure and adolescent stress on the response to arthritis challenge in adult female rats. 2022 Feb 17

Tamara S. Bodnar, David Y. Mak, Lesley A. Hill, Linda Ellis, Wayne Yu, Joanne Weinbergn

2021
Multifunctional Antibiotic-Host Defense Peptid Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response. 2021 Nov 16.

Etayash, H., Alford, M., et al. Journal of Medicinal Chemistry.

2021
SU5416 plus hypoxia but not selective VEGFR2 inhibition with cabozantinib plus hypoxia induces pulmonary hypertension in rats: potential role of BMPR2 signaling. 2021 June 1.

Sitapara, R., Sugarragchaa, C., Zisman, L.S.. Pulmonary Circulation.

2021
Experimental high thoracic spinal cord injury impairs the cardiac and cerebrovascular response to orthostatic challenge in rats. 2021 Sept 23.

Brian D. Hayes, Mary Pauline Mona Fossey, Malihe-Sadat Poormasjedi-Meibod, Erin Erskine, Jan Elaine Soriano, Berkeley Scott, Ryan Rosentreter, David J. Granville, Aaron A. Phillips, and Christopher R. West.

2021
Dnj1 Promotes Virulence in Cryptococcus neoformans by Maintaining Robust Endoplasmic Reticulum Homeostasis Under Temperature Stress. 2021 Sept 10.

Linda C. Horianopoulos, Christopher W. J. Lee, Guanggan Hu, Mélissa Caza, and James W. Kronstad

2021
Developmental Timing of High-Fat Diet Exposure Impacts Glucose Homeostasis in Mice in a Sex-Specific Manner. 2021 Sept 20.

Maria M. Glavas, Ann Y. Lee, Ian Miao, Fan Yang, Majid Mojibian, Shannon M. O’Dwyer, Timothy J. Kieffert.

2021
Bacterial–fungal interactions in the neonatal gut influence asthma outcomes later in life. 2021 Apr 20.

Hayes, B.D., Fossey, M.P..et al.American Journal of Physiology-Heart and Circulatory Physiology..
Rozlyn CT Boutin, Charisse Petersen, Sarah E Woodward, Antonio Serapio-Palacios, Tahereh Bozorgmehr, Rachelle Loo, Alina Chalanuchpong, Mihai Cirstea, Bernard Lo, Kelsey E Huus, Weronika Barcik, Meghan B Azad, Allan B Becker, Piush J Mandhane, Theo J Moraes, Malcolm R Sears, Padmaja Subbarao, Kelly M McNagny, Stuart E Turvey, and B Brett Finlay.

2021
Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies. 2021 March 12.

Alford, M.A., Choi, K.G., et al. Frontiers.

2021
Brain injury after 50 h of lung-protective mechanical ventilation in a preclinical model. 2021 March 3.

Bassi, T.G., Rohrs, E.C., Fernandez, K.C. et al. Sci Rep.

DOI Link
2021
Early overnutrition in male mice negates metabolic benefits of a diet high in monounsaturated and omega-3 fats. 2021 July 7.

Glavas, M.M., Hui, Q., Miao, I. et al. Sci Rep.

DOI Link
2021
Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodenegeration. 2021 Oct 12.

Komal Sodhi, Rebecca Pratt, et al. iScience.

DOI Link
2021
Transvenous Diaphragm Neurostimulation Mitigates Ventilation-associated Brain Injury. 2021 Dec 15.

Thiago G. Bassi, Elizabeth C. Rohrs, Karl C. Fernandez, Marlena Ornowska, Michelle Nicholas, Matt Gani, Doug Evans, and Steven C. Reynolds.

DOI Link
2021
Anti-HSP47 siRNA lipid nanoparticle ND-L02-s0201 reverses interstitial pulmonary fibrosis in preclinical rat models. Apr 2021, 7.

Yun Liu, Jian Liu, et al. ERJ Open Research.

DOI Link
2021
Cardiac Oxidative Signaling and Physiological Hypertrophy in the Na/K-ATPase α1s/sα2s/s Mouse Model of High Affinity for Cardiotonic Steroids. 2021, Mar 27.

Marck, P.V.; Pessoa, M.T.; Xu, Y.; Kutz, L.C.; Collins, D.M.; Yan, Y.; King, C.; Wang, X.; Duan, Q.; Cai, L.;.

DOI Link
2020
In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)6-NH2 and Lau-(Lys-βNspe)6-NH2 Against PMA-Induced Acute Inflammation. 2020 Aug 28.

Wu BC, Skovbakke SL, Masoudi H, Hancock REW and Franzyk H.

DOI Link
2020
Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure.2020 Jan.

Ibrahim, M., MacFarlane, E.M., Matteo, G. et al.

DOI Link
2020
AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects. 2020 June 29.

Ramzy, A., Tudurí, E., Glavas, M.M. et al.

DOI Link
2020
Dietary Intervention Reverses Fatty Liver and Altered Gut Microbiota during Early-Life Undernutrition. 2020 Sept 08.

K. C. Bauer, K. E. Huus, E. M. Brown, T. Bozorgmehr, C. Petersen, M. S. Cirstea, S. E. Woodward, J. McCoy, J. Hun, R. Pamplona, V. Ayala, and B. B. Finlay.

DOI Link
2020
Revisiting Proinsulin Processing: Evidence That Human β-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3 but Not PC2. Jul 2020.

Adam R, Ali A, Timothy J. K.

DOI Link
2020
Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease. 2020 June 10.

Refaeli, I., Hughes, M.R., Wong, A.K. et al.

DOI Link
2020
Rorqual whale nasal plugs: protecting the respiratory tract against water entry and barotrauma. 2020 Feb 17.

Kelsey N. Gil, Margo A. Lillie, A. Wayne Vogl, Robert E. Shadwick.

DOI Link
2019
Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion. 2019 Nov 19.

Bharat Joshi, Judy Pawling, Jay Shankar, Karina Pacholczyk, Yohan Kim, Wynn Tran, Fanrui Meng, Anas M. Abdel Rahman, Leonard J. Foster, Hon S. Leong, James W. Dennis, Ivan R. Nabi.

DOI Link
2019
Intravenous immunoglobulin (IVIg) or IVIg-treated macrophages reduce DSS-induced colitis by inducing macrophage IL-10 production. 2019 May 17.

Kozicky LK, Menzies SC, Hotte N, Madsen KL, Sly LM.

DOI Link
2019
Pancreas-specific miR-216a regulates proliferation and endocrine and exocrine cell function in vivo. 2019 Oct 7.

Suheda E, Cara E. E, Adam R, Maria M. G, Shannon O, Sandra P, Tom W, Janice P, Jennifer E. B, Michael J. R, Robert K. B, Travis D. W, Janel L. K, Stephan H, Timothy J. K.

DOI Link
2019
Radioembolization of Hepatocellular Carcinoma with Built-In Dosimetry: First in vivo Results with Uniformly-Sized, Biodegradable Microspheres Labeled with 188Re. 2019 Jan 25.

De La Vega JC, Esquinas PL, Rodríguez-Rodríguez C, Bokharaei M, Moskalev I, Liu D, Saatchi K, Häfeli UO.

DOI Link
2019
Metabolic Syndrome and Salt-Sensitive Hypertension in Polygenic Obese TALLYHO/JngJ Mice: Role of Na/K-ATPase Signaling. 2019 Jul 16.

Yan Y, Wang J, Chaudhry MA, et al.

DOI Link
2019
Early overnutrition reduces Pdx1 expression and induces β cell failure in Swiss Webster mice. 2019 Mar 6.

Glavas MM, Hui Q, Tudurí E, Erener S, Kasteel NL, Johnson JD, Kieffer TJ.

DOI Link
2018
Carbamazepine, a beta-cell protecting drug, reduces type 1 diabetes incidence in NOD mice. 2018 Mar 15.

Lee, J.T.C., Shanina, I., Chu, Y.N. et al.

DOI Link
2018
Insulin-Deficient Mouse β-Cells Do Not Fully Maturebut Can Be Remedied Through Insulin Replacement by Islet Transplantation. 2018 Jan 1.

Ramzy A, Mojibian M, Kieffer TJ.

DOI Link
2018
Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus. 2018 April 2.

Taylor Meadows KR, Steinberg MW, Clemons B, Stokes ME, Opiteck GJ, Peach R, Scott FL.

DOI Link
2018
Histology of resin vehicles and oleoresin terpene composition of conifer seeds. 2018 Jun 26.

Kshatriya K, Whitehill J, Madilao L, Henderson H, Kermode A, Kolotelo D, Bohlmann J.

DOI Link
2018
Adipose Tissue Expression of PACAP, VIP, and Their Receptors in Response to Cold Stress. 2018 jul 7.

Cline D, Short L, Forster M, Gray S.

DOI Link
2018
Interactive effects of salinity and temperature acclimation on gill morphology and gene expression in threespine stickleback. 2018 July.

Gibbons T, McBryan T, Schulte P.

DOI Link
2018
Image Analysis and histochemistry to identify mobile stem resources for seed production in soybean.

Alerding A, Irvine M, Cunicelli M, Waalkes M, Hill E, Rowe R. 2018 Aug 2.

DOI Link
2018
Pilot Study to Evaluate the Association Between the Length of the Luteal Phase and Estrous Activity Detected by Automated Activity Monitoring in Dairy Cows. 2018 Aug 31.

Denis-Robichaud J, LeBlanc S, Jones-Bitton A, Silper B, Cerri R.

DOI Link
2017
Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes. 2017 Oct.

Neumann UH, Ho JSS, Chen S, Tam YYC, Cullis PR, Kieffer TJ.

DOI Link
2017
Rapid melanoma induction in mice expressing oncogenic BrafV600E using Mitf-cre. 2017 Dec, 20.

Urtatiz O, Samani AMV, Kopp JL, Van Raamsdonk C.

DOI Link
2017
Magnetically-actuated drug delivery device (MADDD) for minimally invasive treatment of prostate cancer: An in vivo animal pilot study. 2017 May.

Struss WJ, Tan Z, Zachkani, Moskalev I, Jackson JK, Shademani A, D’Costa N, Raven P, Frees S, Chavez-Munoz C, Chiao M, So A.

DOI Link
2017
Efficacy of Postnatal In Vivo Nonsense Suppression Therapy in a Pax6 Mouse Model of Aniridia. 2017 June, 16.

Wang X, Gregory-Evans K, Wasan KM, Sivak O, Shan X, Gregory-Evans CY.

DOI Link
2017
Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia. 2017 Apr, 11.

D’souza AM, Kieffer TJ.

DOI Link
2017
Age at injury and genotype modify acute inflammatory and neurofilament-light responses to mild CHIMERA traumatic brain injury in wild-type and APP/PS1 mice. 2017 Dec 18.

Cheng WH, Stukas S, Martens K, Namjoshi D, Button E, Wilkinson A, Bashir A, Robert J, Cripton P, Wellington C.

DOI Link
2017
Stem growth during seed production in soybean: Implications for pod yield. 2017 Dec 19.

Alerding A, Waalkes M, Hill E, Rowe R, Parsons G.

DOI Link
2016
Small Intestine Early Innate Immunity Response during Intestinal Colonization by Escherichia coli Depends on Its Extra-Intestinal Virulence Status. 2016 Apr 20.

Tourret J, Willing BP, Croxen MA, Dufour N, Dion S, Wachtel S, Denamur E, Finlay BB. PLoS One.

DOI Link
2016
Astrocytes promote glioma invasion via the gap junction protein connexin43. 2016 Mar 24.

Sin WC, Aftab Q, Bechberger JF, Leung JH, Chen H, Naus CC.

DOI Link
2015
The Human Dental Pulp Proteome and N‑Terminome: Levering the Unexplored Potential of Semitryptic Peptides Enriched by TAILS to Identify Missing Proteins in the Human Proteome Project in Underexplored Tissues. 2015 Sep, 4.

Eckhard U, Marino G, Abbey SR, Tharmarajah G, Matthew I, Overall CM. J Proteome Res.

DOI Link
2015
Self-propelled particles that transport cargo through flowing blood and halt hemorrhage. 2015 Oct, 2.

Baylis JR, Yeon JH, Thomson MH, Kazerooni A, Wang X, St John AE, Lim EB, Chien D, Lee A, Zhang JQ, Piret JM, Machan LS, Burke TF, White NJ, Kastrup CJ. Sci Adv.

DOI Link
2015
Podoplanin: a marker for reactive gliosis in gliomas and brain injury. 2015 Jan.

Kolar K, Freitas-Andrade M, Bechberger JF, Krishnan H, Goldberg GS, Naus CC, Sin WC.

DOI Link